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Key Documents

C7628

Sigma-Aldrich

5β-Cholanic acid

≥99% (TLC)

Synonym(s):

Ursocholanic acid

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About This Item

Empirical Formula (Hill Notation):
C24H40O2
CAS Number:
Molecular Weight:
360.57
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥99% (TLC)

form

powder

SMILES string

[H]C12CCCCC1(C)C3CCC4(C)C(CCC4C3CC2)[C@@H](C)CCC(O)=O

InChI

1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)

InChI key

RPKLZQLYODPWTM-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Nathan A Ledeboer et al.
Journal of bacteriology, 187(9), 3214-3226 (2005-04-20)
Recently, we demonstrated that Salmonella enterica serovar Typhimurium can form biofilm on HEp-2 cells in a type 1 fimbria-dependent manner. Previous work on Salmonella exopolysaccharide (EPS) in biofilm indicated that the EPS composition can vary based upon the substratum on
Jin Hee Na et al.
Journal of controlled release : official journal of the Controlled Release Society, 163(1), 2-9 (2012-08-01)
To evaluate the tumor targeting efficiency of self-assembled polymeric nanoparticles, four glycol chitosan nanoparticles (CNPs) with different degrees of hydrophobic substitution were prepared by coupling 7.5, 12, 23, and 35 wt.% of 5β-cholanic acid to hydrophilic glycol chitosan polymer (GC).
Kyeongsoon Park et al.
Journal of controlled release : official journal of the Controlled Release Society, 122(3), 305-314 (2007-07-24)
To improve the in vivo tumor targeting characteristics of polymeric nanoparticles, three glycol chitosan (GC-20 kDa, GC-100 kDa, and GC-250 kDa) derivatives with different molecular weights were modified with cholanic acid at the same molar ratio. The resulting amphiphilic glycol
Emilio Bottari et al.
Annali di chimica, 95(7-8), 479-490 (2005-10-21)
To study the composition of sodium cholate solutions, an investigation was carried out at 25 degrees C and in N(CH3)4Cl, as a constant ionic medium, at three different concentrations (W = 0.100; 0.500 and 0.800 mol dm(-3)). Electromotive force measurements
Allan D Heibein et al.
BMC cancer, 12, 381-381 (2012-09-04)
Since proteins involved in chemotherapy drug pharmacokinetics and pharmacodynamics have a strong impact on the uptake, metabolism, and efflux of such drugs, they likely play critical roles in resistance to chemotherapy drugs in cancer patients. To investigate this hypothesis, we

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