Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human, rabbit, rat
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PPP2CA(5515)
Specificity
Recognizes PP2A-subunit alpha and PP2A-subunit beta; does not react with PP1 or other protein phosphatases.
Immunogen
peptide corresponding to the C-terminal amino acid residues 296-309 of human protein phosphatase 2A
Application
Anti-PP2A Antibody, C subunit is an antibody against PP2A for use in IP & WB.
Research Category
Signaling
Neuroscience
Signaling
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurodegenerative Diseases
Neurotransmitters & Receptors
Neurodegenerative Diseases
Quality
routinely evaluated by immunoblot on a rabbit brain cytosol or in a human A431 RIPA cell lysate
Target description
36 kDa
Physical form
Immunoaffinity Purified immunoglobulin in 150mM Tris, pH 7.4, 0.02% sodium azide, 50% glycerol and 5mg/ml BSA
Unpurified
Storage and Stability
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Positive Control Included: Non-Stim A431 Cell Lysate (12-301). Other controls: HeLa whole cel lysate, mouse NIH3T3 cells
Positive Control Included: Non-Stim A431 Cell Lysate (12-301). Other controls: HeLa whole cel lysate, mouse NIH3T3 cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.
John D Imig,Christiana Dimitropoulou,D Sudarshan Reddy,Richard E White,John R Falck
Microcirculation (New York, N.Y. : 1994) (1994)
Neuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's disease.
Lee, KW; Im, JY; Woo, JM; Grosso, H; Kim, YS; Cristovao, AC; Sonsalla, PK; Schuster et al.
Neurotherapeutics null
Postnatal changes in contractile time parameters, calcium regulatory proteins, and phosphatases
Gombosova, I, et al.
The American Journal of Physiology, 274, H2123-H2132 (1998)
Bin Liu et al.
The Journal of endocrinology, 204(2), 209-219 (2009-12-01)
The progesterone (P(4)) rise on proestrous afternoon is associated with dephosphorylation of tyrosine hydroxylase (TH) and reduced TH activity in the stalk-median eminence (SME), which contributes to the proestrous prolactin surge in rats. In the present study, we investigated the
N Begum et al.
The Journal of biological chemistry, 271(49), 31166-31171 (1996-12-06)
In this study, we examined the mechanism of recently reported inactivation of protein phosphatase-2A (PP-2A) by insulin (Srinivasan, M., and Begum, N. (1994) J. Biol. Chem. 269, 12514-12520) and its counter-regulation by cAMP agonists. Exposure of L6 myotubes to insulin
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