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TREM2

triggering receptor expressed on myeloid cells 2

Synonyms:
TREM-2, Trem2a, Trem2b, Trem2c
Species:
UniProtKB ID:
Gene ID:
  • Human(54209) Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
  • Mouse(83433) triggering receptor expressed on myeloid cells 2
  • Rat(301227) triggering receptor expressed on myeloid cells 2
  • sheep(101105447) triggering receptor expressed on myeloid cells 2
  • cow(506467) triggering receptor expressed on myeloid cells 2
  • domestic cat(101099297) triggering receptor expressed on myeloid cells 2
  • dog(608965) triggering receptor expressed on myeloid cells 2
  • chicken(419920) triggering receptor expressed on myeloid cells 2
  • naked mole-rat(101717064) triggering receptor expressed on myeloid cells 2
  • domestic guinea pig(100720722) triggering receptor expressed on myeloid cells 2

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Human TREM-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TREM-2 Antibody, clone 78, clone 78, from rat,
Species Reactivity
human, mouse, rat
Application
flow cytometry
immunocytochemistry

immunoprecipitation (IP)

inhibition assay

western blot
Anti-TREM-2, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TREM-2 Antibody, clone 10H4.2, clone 10H4.2, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TREM2, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Anti-TREM2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
TREM2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TREM2,
Species
human
MISSION® esiRNA, targeting mouse Trem2,
Species
mouse