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Merck

TLR1

toll-like receptor 1

Synonyms:
CD281, TIL, TIL. LPRS5, rsc786
Species:
UniProtKB ID:
Gene ID:
  • Human(7096) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21897) toll-like receptor 1
  • Rat(305354) toll-like receptor 1
  • domestic guinea pig(100732850) toll-like receptor 1
  • Goat(100861260) toll-like receptor 1
  • Zebrafish(403127) toll-like receptor 1
  • Horse(100049577) toll-like receptor 1
  • domestic cat(493660) toll-like receptor 1
  • sheep(554261) toll-like receptor 1
  • cow(574090) toll-like receptor 1
  • naked mole-rat(101717639) toll-like receptor 1
  • dog(488834) toll-like receptor 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Human TLR1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TLR1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry

western blot
Anti-TLR1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-TLR1 (AB2) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TLR1,
Species
human
MISSION® esiRNA, targeting human TLR1 (2),
Species
human
MISSION® esiRNA, targeting mouse Tlr1,
Species
mouse