Skip to Content
Merck

RNF7

ring finger protein 7

Synonyms:
CKBBP1, ROC2, SAG
Species:
UniProtKB ID:
Gene ID:
  • Human(9616) Summary: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19823) ring finger protein 7
  • Rat(300948) ring finger protein 7
  • naked mole-rat(101696646) ring finger protein 7
  • domestic guinea pig(100735307) ring finger protein 7
  • sheep(101106816) ring finger protein 7
  • chicken(424781) ring finger protein 7
  • dog(477097) ring finger protein 7
  • domestic cat(101097835) ring finger protein 7
  • Zebrafish(503534) ring finger protein 7

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RNF7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-RNF7 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot

Proteins

Product Number
Description
Species
PrEST Antigen RNF7, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RNF7 (2),
Species
human
MISSION® esiRNA, targeting human RNF7 (1),
Species
human