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Merck

NDUFA1

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

Synonyms:
CI-MWFE, MWFE, ZNF183
Species:
UniProtKB ID:
Gene ID:
  • Human(4694) Summary: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]
  • Mouse(54405) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • Rat(363441) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • dog(481033) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • domestic cat(101085609) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • chicken(772150) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • naked mole-rat(101713738) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • Zebrafish(415243) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • cow(327673) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • sheep(100216464) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 3B9-1A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NDUFA1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Species
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NDUFA1,
Species
human