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LRBA

LPS-responsive vesicle trafficking, beach and anchor containing

Synonyms:
BGL, CDC4L, CVID8, LAB300, LBA
Species:
UniProtKB ID:
Gene ID:
  • Human(987) Summary: The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
  • Mouse(80877) LPS-responsive beige-like anchor
  • Rat(361975) LPS-responsive vesicle trafficking, beach and anchor containing
  • Zebrafish(100317557) LPS-responsive vesicle trafficking, beach and anchor containing
  • chicken(422476) LPS-responsive vesicle trafficking, beach and anchor containing
  • dog(475463) LPS-responsive vesicle trafficking, beach and anchor containing
  • domestic cat(101093432) LPS-responsive vesicle trafficking, beach and anchor containing
  • domestic guinea pig(100721090) LPS-responsive vesicle trafficking, beach and anchor containing
  • cow(524279) LPS-responsive vesicle trafficking, beach and anchor containing
  • sheep(101106365) LPS-responsive vesicle trafficking, beach and anchor containing
  • naked mole-rat(101711663) LPS-responsive vesicle trafficking, beach and anchor containing
  • Horse(100062459) LPS-responsive vesicle trafficking, beach and anchor containing

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LRBA Antibody, clone 2D4.1, clone 2D4.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-LRBA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-LRBA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human
Application
immunohistochemistry
Anti-LRBA Antibody, clone 3H22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
flow cytometry
immunocytochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LRBA,
Species
human