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Merck

GABRQ

gamma-aminobutyric acid (GABA) A receptor, theta

Synonyms:
THETA
Species:
UniProtKB ID:
Gene ID:
  • Human(55879) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3). [provided by RefSeq, Nov 2009]
  • Mouse(57249) gamma-aminobutyric acid (GABA) A receptor, subunit theta
  • Rat(65187) gamma-aminobutyric acid (GABA) A receptor, theta
  • chicken(396288) gamma-aminobutyric acid (GABA) A receptor, theta
  • Horse(100063455) gamma-aminobutyric acid (GABA) A receptor, theta
  • cow(527180) gamma-aminobutyric acid (GABA) receptor, theta
  • dog(492225) gamma-aminobutyric acid (GABA) A receptor, theta
  • sheep(101113305) gamma-aminobutyric acid (GABA) A receptor, theta
  • domestic cat(101099698) gamma-aminobutyric acid (GABA) A receptor, theta
  • domestic guinea pig(100729123) gamma-aminobutyric acid (GABA) A receptor, theta
  • naked mole-rat(101714872) gamma-aminobutyric acid (GABA) A receptor, theta
  • Domestic Rabbit(100352807) gamma-aminobutyric acid (GABA) A receptor, theta

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Small Molecule - Agonist

Product Number
Description
Species
Meprobamate, United States Pharmacopeia (USP) Reference Standard,
Species
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Oxazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Oxazepam for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Triazolam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Lorazepam for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Lorazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
2,6-Diisopropylphenol, 97%,
Species
human
Flumazenil, >99% (HPLC), solid,
Species
rat, human
5α-Pregnan-3α-ol-20-one, solid,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gabrq,
Species
mouse
MISSION® esiRNA, targeting human GABRQ (2),
Species
human
MISSION® esiRNA, targeting human GABRQ (1),
Species
human