ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonyms:
ABC30, CMOAT, DJS, MRP2, cMRP
Species:
Human ABCC2 (1244), Mouse Abcc2 (12780), Rat Abcc2 (25303), sheep ABCC2 (101119776), Horse ABCC2 (100060654), naked mole-rat Abcc2 (101716089), domestic guinea pig Abcc2 (100718828), cow ABCC2 (520925), domestic cat ABCC2 (101085924), dog ABCC2 (403632) ...More
UniProtKB ID:
Gene ID:
- Human(1244) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
- Mouse(12780) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- Rat(25303) ATP-binding cassette, subfamily C (CFTR/MRP), member 2
- sheep(101119776) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- Horse(100060654) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- naked mole-rat(101716089) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- domestic guinea pig(100718828) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- cow(520925) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- domestic cat(101085924) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- dog(403632) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- chicken(423828) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- Zebrafish(393561) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ABCC2 antibody produced in mouse, clone 2H6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-MRP2 Antibody, clone M2 I-4, culture supernatant, clone M2 I-4, Chemicon®,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MRP2 antibody, Mouse monoclonal, clone CPR96, purified from hybridoma cell culture,
Species Reactivity
human
Application
ELISA
microarray
western blot
microarray
western blot
Anti-MRP2 Antibody, clone 1B2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-MRP2 Antibody, CT, clone M2 III-6, culture supernatant, clone M2 III-6, Chemicon®,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Cell Lines
Kits
Product Number
Description
Species
Proteins
esiRNA
Product Number
Description
Species