ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
Synonyms:
ABC-1, ABC1, CERP, HDLDT1, TGD
Species:
Human ABCA1 (19), Mouse Abca1 (11303), Rat Abca1 (313210), chicken ABCA1 (373945), cow ABCA1 (535379), sheep ABCA1 (101119015), domestic cat ABCA1 (101083885), Horse ABCA1 (100054241), dog ABCA1 (481651), Thale Cress ABCA1 (818768) ...More
UniProtKB ID:
Gene ID:
- Human(19) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
- Mouse(11303) ATP-binding cassette, sub-family A (ABC1), member 1
- Rat(313210) ATP-binding cassette, subfamily A (ABC1), member 1
- chicken(373945) ATP-binding cassette, sub-family A (ABC1), member 1
- cow(535379) ATP-binding cassette, sub-family A (ABC1), member 1
- sheep(101119015) ATP-binding cassette, sub-family A (ABC1), member 1
- domestic cat(101083885) ATP-binding cassette, sub-family A (ABC1), member 1
- Horse(100054241) ATP-binding cassette, sub-family A (ABC1), member 1
- dog(481651) ATP-binding cassette, sub-family A (ABC1), member 1
- Thale Cress(818768) ABC transporter A family member 1
- naked mole-rat(101704546) ATP-binding cassette, sub-family A (ABC1), member 1
- domestic guinea pig(100720792) ATP-binding cassette, sub-family A (ABC1), member 1
- Domestic Rabbit(100356765) ATP-binding cassette, sub-family A (ABC1), member 1
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Small Molecule - Agonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ABCA1 antibody produced in mouse, clone 1H4, ascites fluid,
Species Reactivity
human
Application
ELISA
Anti-ABCA1, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-ABCA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-ABCA1 Antibody, clone AB.H10, clone AB.H10, Chemicon®, from mouse,
Species Reactivity
chicken, human, mouse
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-ABCA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Small Molecule - Inhibitor
esiRNA
Product Number
Description
Species