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Locomotion of Micromotors Due to Liposome Disintegration.

Langmuir : the ACS journal of surfaces and colloids (2020-02-26)
Federico Mazur, Marina Fernández-Medina, Noga Gal, Ondrej Hovorka, Rona Chandrawati, Brigitte Städler
ABSTRACT

Synthetic micromotors are evaluated extensively in a range of biomedical, microscale transport, and environmental applications. Fundamental insight into micromotors that exhibit locomotion due to triggered disintegration of their associated liposomes is provided. Directed self-propulsion is observed when the lipid vesicles are solubilized using Triton X-100 (TX) and bile at sufficiently high concentrations. Directional motion, initiated by a propagating TX or bile gradient, is found when using a sufficiently high concentration of solubilization agents. On the other hand, a low bile concentration results in short-term reverse directional motion. The experimental and theoretical considerations offer valid fundamental understanding to complement the list of explored locomotion mechanisms for micromotors.

MATERIALS
Product Number
Brand
Product Description

Avanti
16:0 NBD PE, Avanti Research - A Croda Brand, powder
Avanti
16:0 NBD PE, Avanti Research - A Croda Brand 810144C