U2625
Uric acid
≥99%, crystalline
Synonym(s):
2,6,8-Trihydroxypurine
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All Photos(4)
About This Item
Empirical Formula (Hill Notation):
C5H4N4O3
CAS Number:
Molecular Weight:
168.11
Beilstein:
156158
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.55
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Assay
≥99%
form
crystalline
mp
>300 °C (lit.)
SMILES string
O=C1NC(=O)C2=C(N1)NC(=O)N2
InChI
1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
InChI key
LEHOTFFKMJEONL-UHFFFAOYSA-N
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Application
Uric acid has been used:
- in inducing hyperuricemia in mice
- as a component of digestion fluid for the simulation of in vitro human digestion model
- in selectivity test of the glucose sensor in sweat-based diabetes monitoring
Biochem/physiol Actions
Uric acid is an insoluble catabolite produced by adenine and guanine metabolism. Accumulation of uric acid leads to gout, hyperuricemia, arthritis and renal failure. Elevated uric acid levels contributes to hypertension and pathogenesis of cardiovascular disease. Low uric acid levels associated with Parkinson′s disease and multiple sclerosis, may elicit protective functionality. High levels of uric acid in patients with chronic obstructive pulmonary disease (COPD) may serve as potential marker for diagnosis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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