Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

N1786

Sigma-Aldrich

NSC 95397

≥97% (HPLC)

Synonym(s):

2,3-Bis[(2-hydroxyethyl)thio]-1,4-naphthoquinone

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C14H14O4S2
CAS Number:
93718-83-3
Molecular Weight:
310.39
MDL number:
MFCD04040032
UNSPSC Code:
12352200
PubChem Substance ID:
24278484
NACRES:
NA.77

Quality Level

100

Assay

≥97% (HPLC)

form

powder

color

orange, solid

solubility

DMSO: 16 mg/mL

storage temp.

−20°C

SMILES string

OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O

InChI

1S/C14H14O4S2/c15-5-7-19-13-11(17)9-3-1-2-4-10(9)12(18)14(13)20-8-6-16/h1-4,15-16H,5-8H2

InChI key

MAASHDQFQDDECQ-UHFFFAOYSA-N

Gene Information

human ... CDC25A(993) , CDC25B(994) , CDC25C(995)

Biochem/physiol Actions

Irreversible Cdc25 dual specificity phosphatase inhibitor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Sodium Orthovanadate A broad spectrum potent inhibitor of protein tyrosine phosphatases.

Sigma-Aldrich

567540

Sodium Orthovanadate

Qin Zhou et al.
PloS one, 5(10), e13538-e13538 (2010-11-05)
Keratin polypeptide 19 (K19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. Although K19 is known to be phosphorylated on tyrosine residue(s), conclusive site-specific characterization of these residue(s) and identification potential kinases that
Lei Jin et al.
Communications biology, 3(1), 349-349 (2020-07-06)
Angiogenesis is required for tissue repair; but abnormal angiogenesis or neovascularization (NV) causes diseases in the eye. The avascular status in the cornea is a prerequisite for corneal clarity and thought to be maintained by the equilibrium between proangiogenic and
Hong Li et al.
International journal of biological sciences, 16(7), 1107-1120 (2020-03-17)
Traumatic brain injury (TBI) induces an acute inflammatory response in the central nervous system that involves both resident and peripheral immune cells. The ensuing chronic neuroinflammation causes cell death and tissue damage and may contribute to neurodegeneration. The molecular mechanisms
Yan Han et al.
Journal of proteome research, 17(1), 579-589 (2017-12-21)
The new strategy for chemical toxicity testing and modeling is to use in vitro human cell-based assays in conjunction with quantitative high-throughput screening (qHTS) technology, to identify molecular mechanisms and predict in vivo responses. Stem cells are more physiologically relevant
Guan-Hao Zhao et al.
Biochemical pharmacology, 172, 113741-113741 (2019-12-10)
Na+/K+-ATPase α1 was reported to directly interact with and recruit FGF2 (fibroblast growth factor 2), a vital cell signaling protein implicated in angiogenesis, to the inner plasma membrane for subsequent secretion. Cardenolides, a class of cardiac glycosides, were reported to
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service