E6910
Pioglitazone hydrochloride
≥98% (HPLC), powder, hepatic gluconeogenesis blocker
Synonym(s):
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride
About This Item
Recommended Products
product name
Pioglitazone hydrochloride, ≥98% (HPLC)
Assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: ≥10 mg/mL
originator
Takeda
storage temp.
room temp
SMILES string
Cl.CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
InChI
1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
InChI key
GHUUBYQTCDQWRA-UHFFFAOYSA-N
Gene Information
human ... PPARG(5468)
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General description
Application
- to administer to mice model and treated the hepatoma cell line to study its effect on regulating insulin-degrading enzyme (IDE) in diet-induced obese (DIO) C57BL/6 mice
- in drug preparation to analyze its effects on shortening and calcium transport in ventricular myocytes from the Goto-Kakizaki (GK) type 2 diabetic rat
- to treat HepG2 cells with peroxisome proliferator-activated receptor γ (PPARγ) agonists to examine its effect on TOMM40-, APOE- and APOC1-mRNA levels
Biochem/physiol Actions
Features and Benefits
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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