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C4479

Sigma-Aldrich

9-Cyclopentyladenine monomethanesulfonate

≥98% (HPLC)

Synonym(s):

9-CP-Ade mesylate, 9-Cyclopentyladenine mesylate

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About This Item

Linear Formula:
C10H13N5 · CH3SO3H
CAS Number:
189639-09-6
Molecular Weight:
299.35
MDL number:
MFCD11045955
UNSPSC Code:
41106305
PubChem Substance ID:
24278313
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

mp

180-183 °C (lit.)

solubility

H2O: 5 mg/mL, clear

storage temp.

room temp

SMILES string

CS(O)(=O)=O.Nc1ncnc2n(cnc12)C3CCCC3

InChI

1S/C10H13N5.CH4O3S/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-7;1-5(2,3)4/h5-7H,1-4H2,(H2,11,12,13);1H3,(H,2,3,4)

InChI key

AJMDRSJHCYQPQI-UHFFFAOYSA-N

Biochem/physiol Actions

A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain. IC50 = 100 μM in detergent-dispersed rat brain preparation.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yu Zhang et al.
Frontiers in neuroscience, 14, 364-364 (2020-05-16)
Electrical synapses between neurons exhibit a high degree of plasticity, which makes critical contributions to neuronal communication. The GABAergic parvalbumin-expressing (PV+) neurons in the thalamic reticular nucleus (TRN) interact with each other through electrical and chemical synapses. Plasticity of electrical

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