Skip to Content
Merck
All Photos(2)

Documents

200-05N

Sigma-Aldrich

Human Umbilical Vein Endothelial Cells: HUVEC, neonatal

Synonym(s):

HUVEC cells

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41106514
NACRES:
NA.81

biological source

human umbilicus (normal veins)

Quality Level

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 46

morphology

Endothelial

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

arthritis; diabetes; cancer; cardiovascular diseases

shipped in

dry ice

storage temp.

−196°C

General description

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

Human Umbilical Vein Endothelial Cells (HUVEC) provide a classic model system to study many aspects of endothelial function and disease, such as normal, abnormal and tumor-associated angiogenesis, oxidative stress, hypoxia and inflammation related pathways in endothelia under normal and pathological conditions, cardiovascular-related complications associated with various diseases, mode of action and cardiovascular protection effects of various compounds, etc.

Cell Line Origin

Vein

Application

angiogenesis, cell signaling pathways, migration, invasion, growth factors, tube formation, vascular homeostasis, modulation of blood vessel tone, regulate cell grwoth and ECM deposition, vasculoregulation

Components

Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO

Preparation Note

  • Primary culture, >500,000 cells in Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 16 doublings

Subculture Routine

Please refer to the HUVEC Culture Protocol.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Wei Yan et al.
Frontiers in cell and developmental biology, 9, 616306-616306 (2021-04-09)
Oral squamous cell carcinoma (OSCC), accounting for two-thirds of head and neck cancer, is characterized by poor prognosis and a high rate of mortality. Exosomes have emerged as potential molecule-shuttle in intercellular communication, thereby regulating the physiological processes of recipient
Ziwei Tang et al.
International journal of endocrinology, 2021, 5575927-5575927 (2021-07-10)
It has been increasingly appreciated that G protein-coupled estrogen receptor 1 (GPER1) mediates both proinflammatory and anti-inflammatory response of estrogen. It is also involved in some rapid vascular effects of aldosterone in a mineralocorticoid receptor (MR) independent manner. However, whether
Clarisse Roblin et al.
International journal of molecular sciences, 22(6) (2021-04-04)
The world is on the verge of a major antibiotic crisis as the emergence of resistant bacteria is increasing, and very few novel molecules have been discovered since the 1960s. In this context, scientists have been exploring alternatives to conventional
Yi-Ting Yeh et al.
PLoS pathogens, 18(3), e1010309-e1010309 (2022-03-23)
The eggs of the parasitic blood fluke, Schistosoma, are the main drivers of the chronic pathologies associated with schistosomiasis, a disease of poverty afflicting approximately 220 million people worldwide. Eggs laid by Schistosoma mansoni in the bloodstream of the host

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service