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32133

Supelco

Desoxycarbadox

VETRANAL®, analytical standard

Synonym(s):

2-(2-Quinoxalinylmethylene)hydrazinecarboxylic acid methyl ester, Methyl 3-(2-quinoxalinylmethylene)carbazate

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About This Item

Empirical Formula (Hill Notation):
C11H10N4O2
CAS Number:
55456-55-8
Molecular Weight:
230.22
Beilstein:
799004
MDL number:
MFCD01722570
UNSPSC Code:
41116107
PubChem Substance ID:
329754057
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

COC(=O)N\N=C\c1cnc2ccccc2n1

InChI

1S/C11H10N4O2/c1-17-11(16)15-13-7-8-6-12-9-4-2-3-5-10(9)14-8/h2-7H,1H3,(H,15,16)/b13-7+

InChI key

SOEMFPLGOUBPJQ-NTUHNPAUSA-N

General description

Desoxycarbadox is a metabolite of the antimicrobial growth promoting agent, carbodox.

Application

Desoxycarbadox may be used as a reference standard in the determination of desoxycarbadox in porcine tissue samples using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

H228,H302,H350

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Flam. Sol. 1

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH5539
BCCF0931
BCCD1152
BCBV9345
BCBT1683

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Antimicrobial Therapy in Veterinary Medicine (2013)
G J de Graaf et al.
The Veterinary quarterly, 10(1), 34-41 (1988-01-01)
Concentrations of carbadox and a first metabolite, desoxycarbadox, were measured in contents of the porcine gastrointestinal tract after in-feed administration of carbadox in therapeutic dosages (100-150 ppm). The levels of carbadox in the relevant parts of the gastrointestinal tract were
A I MacIntosh et al.
Journal - Association of Official Analytical Chemists, 68(4), 665-671 (1985-07-01)
A liquid chromatographic method was used to monitor a depletion study of carbadox (and its most important metabolite, desoxycarbadox) in young pigs fed carbadox-treated rations for 1 week. Carbadox was found in blood (20 ppb), blood serum (26 ppb), and
A I MacIntosh et al.
Journal - Association of Official Analytical Chemists, 67(5), 958-962 (1984-09-01)
A liquid chromatographic (LC) method has been developed for the determination of carbadox, desoxycarbadox, and nitrofurazones in the 10-40 ppb range in pork muscle, liver, and kidney tissues. Tissues were homogenized in absolute ethanol, and the homogenates were treated with
G J de Graaf et al.
Journal - Association of Official Analytical Chemists, 68(4), 658-660 (1985-07-01)
A liquid chromatographic method for the assay of carbadox and desoxycarbadox in medicated feeds and porcine stomach and intestinal contents is described. Samples were extracted with dimethylformamide-water and cleaned up on an alumina column. The eluate was chromatographed using either
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