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529265

Sigma-Aldrich

Poly(2-hydroxyethyl methacrylate)

average Mv 20,000

Synonym(s):

Poly(2-HEMA), Poly-HEMA

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About This Item

Linear Formula:
(C6H10O3)n
CAS Number:
25249-16-5
MDL number:
MFCD00084374
UNSPSC Code:
12162002
PubChem Substance ID:
24877667
NACRES:
NA.23

form

powder

mol wt

average Mv 20,000

transition temp

Tg 84.8 °C

density

1.15 g/mL at 25 °C (lit.)

SMILES string

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Application

  • Hydrogen-bonds structure in poly(2-hydroxyethyl methacrylate) studied by temperature-dependent infrared spectroscopy: Investigates the hydrogen-bond structure in poly(2-hydroxyethyl methacrylate) (PHEMA) using temperature-dependent IR spectroscopy. (S Morita, 2014).
  • Transparent and tough poly(2-hydroxyethyl methacrylate) hydrogels prepared in water/IL mixtures: Describes the development of tough and transparent PHEMA hydrogels for potential use in various biomedical applications. (Y Liu et al., 2020).
  • Reduced cell attachment to poly(2-hydroxyethyl methacrylate)-coated ventricular catheters in vitro: Examines how PHEMA coatings can reduce cell attachment, which is beneficial for biomedical devices like catheters. (BW Hanak et al., 2018).
  • Surface modification of poly(2-hydroxyethyl methacrylate) hydrogel for contact lens application: Studies modifications to PHEMA hydrogels to improve their suitability for contact lens applications. (M Kazemi Ashtiani, M Zandi, 2018).

Physical form

Water-swellable polymer. Hydrogel.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Kazım Köse et al.
Artificial cells, nanomedicine, and biotechnology, 41(1), 13-20 (2012-11-01)
The purpose of this article is to synthesize poly(hydroxyethyl methacrylate-N-methacryloyl-(L)-tryptophan) [mPHEMATrp] magnetic nanoparticles for lysozyme purification from chicken egg white. mPHEMATrp nanoparticles (38 nm in diameter) were synthesized by surfactant-free emulsion polymerization. Specific surface area of the mPHEMATrp nanoparticles was
M Rafiqul Islam et al.
Journal of nanoscience and nanotechnology, 13(1), 603-606 (2013-05-08)
Biocompatible magnetic nanocomposites of Fe-AuNPs and poly(2-hydroxylethyl methacrylate) (PHEMA) were employed as a strategic protein immobilization platform. The hybrid magnetic nanocomposites were prepared by applying a 'grafting to' ATRP protocol. Fe-AuNPs having Fe core and Au shell were initially prepared
Yan Fang et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13318-13324 (2012-08-28)
We present a detailed picture to screen general ligands from simple chemicals for fabricating affinity surface to glycosidase enzymes. The surface was constructed by grafting poly(2-hydroxyethyl methacrylate) (PHEMA) brush on SPR gold chip via surface-initiated atom-transfer radical polymerization, after which
Damla Cetin et al.
Journal of materials science. Materials in medicine, 23(11), 2803-2812 (2012-08-09)
The effectiveness of poly(2-hydroxyethyl methacrylate)-gelatin superporous hydrogels (pHEMA-gelatin SPHs) was investigated for bone tissue engineering. The cell culture studies were performed with preosteoblastic MC3T3-E1 cells. Dynamic culture conditions were provided using 100 ml spinner flask rotating at 50 rpm. According
Yunfeng Li et al.
ACS applied materials & interfaces, 5(6), 2126-2132 (2013-02-23)
This paper presents a versatile way to prepare multiscale and gradient patterns of proteins. The protein patterns are fabricated by conjugating proteins covalently on patterns of polymer brush that are prepared by techniques combining colloidal lithography with photolithography, and two-step
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