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426008

Sigma-Aldrich

Carbofuran

98%

Synonym(s):

2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15NO3
CAS Number:
1563-66-2
Molecular Weight:
221.25
Beilstein:
1428746
EC Number:
216-353-0
MDL number:
MFCD00041819
UNSPSC Code:
12352100
PubChem Substance ID:
24866678
NACRES:
NA.22

Assay

98%

form

crystals

mp

150-153 °C (lit.)

SMILES string

CNC(=O)Oc1cccc2CC(C)(C)Oc12

InChI

1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)

InChI key

DUEPRVBVGDRKAG-UHFFFAOYSA-N

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General description

Carbofuran is an anticholinesterase carbamate, which is commonly used as a pesticide. Its literature data on toxicity have been reviewed. The effect from exposure to carbofuran has been investigated on acetylcholinesterase (AChE) activity in the brain and muscle of common carp (Cyprinus carpio). Degradation studies using ozone, UV radiation and advanced oxidation processes (AOPs) and by photocatalytic degradation have been investigated. Ultra high performance liquid chromatography (UHPLC) method to determine the carbofuran in water samples have been developed with satisfactory results.

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H300 + H330,H311,H410

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Degradation of carbofuran by using ozone, UV radiation and advanced oxidation processes.
Benitez FJ, et al.
Journal of Hazardous Materials, 89(1), 51-65 (2002)
Photocatalytic degradation of carbofuran using semiconductor oxides.
Mahalakshmi M, et al.
Journal of Hazardous Materials, 143(1), 240-245 (2007)
Xia Sun et al.
Sensors (Basel, Switzerland), 11(12), 11679-11691 (2012-01-17)
In this paper, an amperometric immunosensor modified with protein A/deposited gold nanocrystals (DpAu) was developed for the ultrasensitive detection of carbofuran residues. First, DpAu were electrodeposited onto the Au electrode surface to absorb protein A (PA) and improve the electrode
Li A Lu et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 47(6), 553-561 (2012-04-13)
Carbofuran, one of the most toxic and biorefractory carbamate compounds, is widely used in insecticides in Taiwan (9-18% of total insecticides production per year). In the present study, a central composite design experiment was used to study the effect of
Luís Pedro de Melo Plese et al.
Chemosphere, 60(2), 149-156 (2005-05-26)
The objectives of this work were estimate the reaction rates of hydrolysis of carbosulfan to carbofuran and subsequent degradation of this last compound in irrigated rice fields, and the respective half life, in aquatic environment and soil solution, by mean
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