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SCP0073

Sigma-Aldrich

Caspase 1 Substrate (ICE), fluorogenic

≥95% (HPLC), lyophilized

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About This Item

Empirical Formula (Hill Notation):
C35H41N5O12
Molecular Weight:
723.73
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Caspase 1 Substrate (ICE), fluorogenic,

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Ac-Tyr-Glu-Val-Asp-AMC

Application

Caspase 1 is a cysteine protease activator of inflammatory processes which may be detected using a variety of chromogenic and fluorogenic peptide substrates build around the YEVD (Tyr-Glu-Val-Asp) sequence. These substrates include: Ac-YEVD-pNa (Ac-Tyr-Glu-Val-Asp-p-nitroanalide), chromogenic and Ac-YEVD-AMC (Ac-Tyr-Glu-Val-Asp-7-amino-4-methylcoumarin), fluorogenic.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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