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SAB4301607

Sigma-Aldrich

Anti-CD63

affinity isolated antibody

Synonym(s):

LAMP-3, ME491, MLA1, OMA81H, TSPAN30

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:25-1:100
western blot: 1:500-1:2000

accession no.

NP_001244318

UniProt accession no.

P08962

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CD63(967)

General description

Cluster of differentiation (CD63) belongs to the tetraspanin family, with four transmembrane domains. It is localised in late endosomes and lysosomes. The gene is located on human chromosome 12q13.2. CD63 is a membrane bound glycoprotein.

Immunogen

Synthetic peptide of human CD63 molecule

Biochem/physiol Actions

Cluster of differentiation (CD63) acts as a platelet activation marker. It plays an important role in regulating cell proliferation, adhesion, motility and differentiation. CD63 acts as a prognostic marker for lung adenocarcinoma. Deficiency of CD63 is associated with Hermansky−Pudlak syndrome (HPS).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dongdong Tian et al.
International journal of molecular medicine, 50(1) (2022-05-28)
Chronic obstructive pulmonary disease (COPD) is one of the major causes of death worldwide today, and its related morbidity has been predicted to show an increase in subsequent years. Recent studies have shown that Danshen, a Chinese herbal medicine, is
Trafficking and function of the tetraspanin CD63
Pols MS and Klumperman J
Experimental Cell Research, 315(9), 1584-1592 (2009)
Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function
Wei ML
Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 19(1), 19-42 (2006)
Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes
De Leeuw RJ, et al.
Human Molecular Genetics, 13(17), 1827-1837 (2004)
Łukasz Zadka et al.
The American journal of pathology, 191(12), 2147-2171 (2021-08-25)
Three-dimensional (3D) imaging and quantitative analysis of extracellular vesicles (EVs) remain largely unexplored, mainly because of limitations in detection techniques. In this study, EVs from patients diagnosed with colorectal cancer (CRC) and ulcerative colitis were examined. To investigate the spatial
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