Skip to Content
Merck
All Photos(1)

Documents

PHR1259

Supelco

Thiabendazole

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Thiabendazole, 2-(4-Thiazolyl)benzimidazole

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C10H7N3S
CAS Number:
Molecular Weight:
201.25
Beilstein:
611403
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. T1410000
traceable to USP 1655000

API family

thiabendazole

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

c1ccc2[nH]c(nc2c1)-c3cscn3

InChI

1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)

InChI key

WJCNZQLZVWNLKY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Thiabendazole is an orally effective broad spectrum anthelmintic and antimycotic drug with limited side-effects.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Thiabendazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and preparations by spectrophotometric, spectrofluorimetric and chromatography techniques.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA9062 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of 81 pharmaceutical drugs by high performance liquid chromatography coupled to mass spectrometry with hybrid triple quadrupole--linear ion trap in different types of water in Serbia
Petrovic M, et al.
The Science of the Total Environment, 468(2), 415-428 (2014)
Development of a spectrofluorimetric method for determination of thiabendazole in tablets
Kucukkolbasi S and Kilic E
Journal of Applied Pharmaceutical Science, 3(2), 19-19 (2013)
Mechanism of action of the fungicide thiabendazole, 2-(4?-thiazolyl) benzimidazole
Allen PM and Gottlieb D
Applied and Environmental Microbiology, 20(6), 919-926 (1970)
Studies on the toxicologic and pharmacologic properties of thiabendazole
Robinson HJ, et al.
Toxicology and Applied Pharmacology, 7(1), 53-63 (1965)
Suely R C Andrade et al.
Journal of pharmaceutical and biomedical analysis, 33(4), 655-665 (2003-11-19)
Three multivariate calibration methods, Principal Component Regression (PCR), the K-matrix method and Q-mode factor analysis followed by varimax and Imbrie's oblique rotations were applied to the simultaneous spectrophotometric determinations of mebendazole (MBZ)-cambendazole (CBZ) and thiabendazole (TBZ)-mebendazole in commercial samples of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service