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Key Documents

C1520000

Chlorhexidine diacetate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Chlorhexidine diacetate salt

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About This Item

Empirical Formula (Hill Notation):
C22H30Cl2N10 · 2C2H4O2
CAS Number:
Molecular Weight:
625.55
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

chlorhexidine

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)

InChI key

WDRFFJWBUDTUCA-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorhexidine diacetate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2

Target Organs

Liver,Teeth

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Manikandan Ekambaram et al.
Journal of dentistry, 42(7), 872-882 (2014-02-25)
To evaluate the effect of adjunctive application of ethanol-wet bonding and chlorhexidine (CHX) with a hydrophobic adhesive on bond durability of fibre posts to intraradicular dentine. Ninety-six extracted human teeth with a single root and root canal were prepared for
Synthesis, characterization and antibacterial properties of dihydroxy quaternary ammonium salts with long chain alkyl bromides.
Liu WS, Wang CH, Sun JF, et al.
Chemical Biology & Drug Design, 85(1), 91-97 (2014)
Manikandan Ekambaram et al.
Journal of dentistry, 42(6), 709-719 (2014-04-16)
To examine the effect of adjunctive application of chlorhexidine (CHX) and ethanol-wet bonding (EWB) on bond durability and nanoleakage of hydrophobic adhesive to sound (SD) and caries-affected dentine (CAD). Dentine surfaces of molars were etched after caries removal and randomly
M G Bueno et al.
Oral diseases, 21(1), 57-65 (2013-11-14)
The antimicrobial action of five drugs incorporated in temporary denture relines on the fungal biofilm was evaluated. A Candida albicans biofilm (SC5314) was formed on specimens (10 × 1 mm) of materials (Trusoft and Softone) modified or not (control) by
R C Beier et al.
Journal of applied microbiology, 118(2), 326-342 (2014-11-29)
To evaluate susceptibility of Pseudomonas aeruginosa veterinary isolates to antibiotics and disinfectants. Pseudomonas aeruginosa isolates collected from dogs (n = 155) and other animals (n = 20) from sixteen states during 1994-2003 were tested for susceptibility. Most isolates were resistant

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