88808

(S)-(+)-1-Methoxy-2-propanol

≥98.5% (sum of enantiomers)

• Synonym(s): (S)-(+)-Propylene glycol 1-methyl ether
• Empirical Formula (Hill Notation): C₄H₁₀O₂
• CAS Number: 26550-55-0
• Molecular Weight: 90.12
• Beilstein: 1718940
• MDL number: MFCD01632588
• UNSPSC Code: 12352112
• PubChem Substance ID: 57653320
• NACRES: NA.22

Properties

• Assay: ≥98.5% (sum of enantiomers)
• form: liquid
• optical activity: [α]20/D +22±2°, c = 10% in chloroform
• refractive index: n20/D 1.403
• density: 0.921 g/mL at 20 °C (lit.)
• SMILES string: COC[C@H](C)O
• InChI: 1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3/t4-/m0/s1
• InChI key: ARXJGSRGQADJSQ-BYPYZUCNSA-N

Description

Application

(S)-(+)-1-Methoxy-2-propanol can be used as a reactant to prepare:

• (S)-1-methoxypropan-2-yl 4-methylbenzenesulfonate by reacting with tosyl chloride in the presence of pyridine.
• Thiazolopyridine urea derivatives.
• Quinazoline derivatives as potential inhibitors of EGFR/HER-2 tyrosine kinases.

Safety Information

• Pictograms: GHS02
• Signal Word: Warning
• Hazard Statements: H226
• Hazard Classifications: Flam. Liq. 3
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 91.4 °F - closed cup
• Flash Point(C): 33 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves