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The molybdenum cofactor.

The Journal of biological chemistry (2013-03-30)
Ralf R Mendel
ABSTRACT

The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase. The biosynthesis of Moco involves the complex interaction of six proteins and is a process of four steps, which also require iron, ATP, and copper. After its synthesis, Moco is distributed, involving Moco-binding proteins. A deficiency in the biosynthesis of Moco has lethal consequences for the respective organisms.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Molybdenum, nanopowder, <100 nm particle size (TEM), 99.8% trace metals basis
Sigma-Aldrich
Molybdenum, powder, 1-5 μm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, powder, <150 μm, 99.99% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 1.0 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, powder, 10 μm, ≥99.95% trace metals basis
Sigma-Aldrich
Molybdenum, powder, <150 μm, 99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 0.025 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 0.1 mm, ≥99.9% trace metals basis
Molybdenum, wire reel, 1000m, diameter 0.035mm, as drawn, 99.95%
Molybdenum, tube, 200mm, outside diameter 6.0mm, inside diameter 4.4mm, wall thickness 0.8mm, 99.9%
Molybdenum, foil, light tested, 50x50mm, thickness 0.006mm, 99.9%
Molybdenum, tube, 100mm, outside diameter 0.5mm, inside diameter 0.38mm, wall thickness 0.06mm, 99.9%
Molybdenum, foil, light tested, 150x150mm, thickness 0.05mm, annealed, 99.9%
Molybdenum, wire reel, 1000m, diameter 0.05mm, annealed, 99.95%
Molybdenum, foil, light tested, 50x50mm, thickness 0.075mm, annealed, 99.9%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.01mm, 99.9%
Molybdenum, foil, light tested, 50x50mm, thickness 0.008mm, 99.9%
Molybdenum, foil, light tested, 25x25mm, thickness 0.009mm, 99.9%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.004mm, 99.9%
Molybdenum, foil, light tested, 29x200mm, thickness 0.0712mm, annealed, 99.9%
Molybdenum, foil, not light tested, 50x50mm, thickness 0.002mm, 99.9%
Molybdenum, foil, not light tested, 150x150mm, thickness 0.05mm, annealed, 99.9%
Molybdenum, insulated wire, 10m, conductor diameter 0.125mm, insulation thickness 0.012mm, polyimide insulation, 99.95%
Molybdenum, foil, light tested, 29x500mm, thickness 0.0712mm, annealed, 99.9%
Molybdenum, foil, light tested, 50x50mm, thickness 0.01mm, 99.9%
Molybdenum, foil, light tested, 29x600mm, thickness 0.0712mm, annealed, 99.9%
Molybdenum, foil, light tested, 25x25mm, thickness 0.01mm, 99.9%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.005mm, 99.9%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.007mm, 99.9%
Molybdenum, microfoil, disks, 25mm, thinness 0.1μm, specific density 92.4μg/cm2, permanent mylar 3.5μm support, 99.9%