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  • Modulation of Interfacial Hydration by Carbonyl Groups in Lipid Membranes.

Modulation of Interfacial Hydration by Carbonyl Groups in Lipid Membranes.

Langmuir : the ACS journal of surfaces and colloids (2020-02-20)
H A Pérez, J P Cejas, A S Rosa, R E Giménez, E A Disalvo, M A Frías
ABSTRACT

The lack of carbonyl groups and the presence of ether bonds give the lipid interphase a different water organization around the phosphate groups that affects the compressibility and electrical properties of lipid membranes. Generalized polarization of 1,2-di-O-tetradecyl-sn-glycero-3-phosphocholine (14:0 diether PC) in correlation with Fourier transform infrared (FTIR) analysis indicates a higher level of polarizability of water molecules in the membrane phase around the phosphate groups both below and above Tm. This reorganization of water promotes a different response in compressibility and dipole moment of the interphase, which is related to different H bonding of water molecules with phosphates (PO) and carbonyl (CO) groups.

MATERIALS
Product Number
Brand
Product Description

Avanti
16:0 PC (DPPC), Avanti Research - A Croda Brand
Avanti
16:0 PC (DPPC), Avanti Research - A Croda Brand
Avanti
14:0 Diether PC, Avanti Research - A Croda Brand 999993P, powder
Avanti
14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform
Avanti
14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder