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Sigma-Aldrich

Ammonium hydroxide solution

28% NH3 in H2O, ≥99.99% trace metals basis

Synonym(s):

Ammonia aqueous, Ammonia water

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About This Item

Linear Formula:
NH4OH
CAS Number:
1336-21-6
Molecular Weight:
35.05
Beilstein:
3587154
MDL number:
MFCD00066650
UNSPSC Code:
12352106
eCl@ss:
38060103
PubChem Substance ID:
329754690
NACRES:
NA.21

Assay

≥99.99% trace metals basis

form

liquid

expl. lim.

27 %

concentration

28% NH3 in H2O

pH

11.7 (20 °C)

density

0.9 g/mL at 25 °C (lit.)
0.9 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

[NH4+].[OH-]

InChI

1S/H3N.H2O/h1H3;1H2

InChI key

VHUUQVKOLVNVRT-UHFFFAOYSA-N

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General description

Ammonium hydroxide solution is also called aqueous ammonia, aqua ammonia, or ammonia water. It is a weak base mainly used as a nitrogen source to prepare other nitrogen-containing organic and inorganic chemicals such as urea, ammonium carbonate, ammonium sulfate, etc.

Application

Ammonium hydroxide solution (28% NH3 in H2O) can be used as:
  • A medium to prepare magnetite (Fe3O4) nanoparticles via a modified controlled chemical coprecipitation method using divalent or trivalent iron salts as iron precursors.      
  • A reagent in ammonolysis.      
  • A solvent to synthesize 1, 4 dihydropyridines via one-pot condensation of an aldehyde and alkyl acetoacetate.

Signal Word

Danger

Hazard Statements

H314,H335,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Konstantin Chingin et al.
Analytical chemistry, 84(15), 6856-6862 (2012-07-12)
We introduce an online multiple-junction capillary isoelectric focusing fractionator (OMJ-CIEF) for separation of biological molecules in solution by pI. In OMJ-CIEF, the separation capillary is divided into seven equal sections joined with each other via tubular Nafion membrane insertions. Each
Mengqi Li et al.
Cell metabolism, 30(3), 508-524 (2019-06-18)
Fructose-1,6-bisphosphate (FBP) aldolase links sensing of declining glucose availability to AMPK activation via the lysosomal pathway. However, how aldolase transmits lack of occupancy by FBP to AMPK activation remains unclear. Here, we show that FBP-unoccupied aldolase interacts with and inhibits
J C Naviaux et al.
Translational psychiatry, 4, e400-e400 (2014-06-18)
Autism spectrum disorders (ASDs) now affect 1-2% of the children born in the United States. Hundreds of genetic, metabolic and environmental factors are known to increase the risk of ASD. Similar factors are known to influence the risk of schizophrenia
Aurélie Periat et al.
Journal of chromatography. A, 1356, 211-220 (2014-07-16)
In this study, the influence of electrospray ionization (ESI) source design on the overall sensitivity achieved in hydrophilic interaction chromatography (HILIC) and reversed phase liquid chromatography (RPLC), was investigated. State-of-the-art triple quadrupole mass analyzers from AB Sciex, Agilent Technologies and
Azza Gramoun et al.
Arthritis research & therapy, 16(3), R131-R131 (2014-06-25)
Rheumatoid arthritis (RA) is a chronic disease causing recurring inflammatory joint attacks. These attacks are characterized by macrophage infiltration contributing to joint destruction. Studies have shown that RA treatment efficacy is correlated to synovial macrophage number. The aim of this
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