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80430

Sigma-Aldrich

Dichlorodimethylsilane

produced by Wacker Chemie AG, Burghausen, Germany, ≥99.0% (GC)

Synonym(s):

Silane M2, DMDCS, Dimethyldichlorosilane

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About This Item

Linear Formula:
(CH3)2SiCl2
CAS Number:
Molecular Weight:
129.06
Beilstein:
605287
EC Number:
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

grade

produced by Wacker Chemie AG, Burghausen, Germany

Quality Level

Assay

≥99.0% (GC)

form

liquid

refractive index

n20/D 1.404 (lit.)

bp

70 °C (lit.)

mp

−76 °C (lit.)

density

1.07 g/mL at 25 °C (lit.)

SMILES string

C[Si](C)(Cl)Cl

InChI

1S/C2H6Cl2Si/c1-5(2,3)4/h1-2H3

InChI key

LIKFHECYJZWXFJ-UHFFFAOYSA-N

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General description

Dichlorodimethylsilane is an organosilicon compound generally used as a protecting group for diols and carbonyl compounds. It is also used as a starting material for the preparation of silicon-based reagents.

Application

Dichlorodimethylsilane can be used:
  • As a silane coupling agent in the synthesis of silica nanoparticles and in their surface modification studies.
  • To prepare polydimethylsiloxane microemulsions by reacting with sodium dodecylpolyoxyethylene sulfate.
  • To prepare a novel heterasumanene where the benzylic carbon atoms of the sumanene are replaced by heteroatom (S, Si) functionalities

Other Notes

prices for bulk quantities on request

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

33.8 °F - closed cup

Flash Point(C)

1 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J M Curran et al.
Biomaterials, 32(21), 4753-4760 (2011-04-15)
Material modifications can be used to induce cell responses, in particular-CH(3) and -NH(2) have shown potential in enhancing the ability of a material to support mesenchymal stem cell (MSC) adhesion and differentiation. Currently this process is variable, due to the
Bernard P Binks et al.
Physical chemistry chemical physics : PCCP, 9(48), 6391-6397 (2007-12-07)
We report measured and calculated oil-ionic liquid, water-ionic liquid and oil-water contact angles on silica surfaces which have been hydrophobised to different extents by silanisation. Based on the idea that the contact angle formed by a liquid-liquid interface with a
T G Ruardy et al.
Journal of biomedical materials research, 29(11), 1415-1423 (1995-11-01)
In this study, adhesion and spreading of human skin fibroblasts on gradient surfaces of dichlorodimethylsilane (DDS) coupled to glass was investigated. Gradient surfaces were prepared by the diffusion technique and characterized by the Wilhelmy plate technique and characterized by the
J Sotres et al.
Journal of dental research, 91(10), 973-978 (2012-08-10)
The pellicle serves as a multifunctional protective layer, providing, e.g., lubrication and remineralization and also acting as a diffusion barrier. In addition, since the formation of the pellicle precedes the adhesion of micro-organisms, it is also important as a conditioning
Niels P Boks et al.
Microbiology (Reading, England), 154(Pt 10), 3122-3133 (2008-10-04)
Using a parallel-plate flow chamber, the hydrodynamic shear forces to prevent bacterial adhesion (F(prev)) and to detach adhering bacteria (F(det)) were evaluated for hydrophilic glass, hydrophobic, dimethyldichlorosilane (DDS)-coated glass and six different bacterial strains, in order to test the following

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