648468

Triton^™ X-114 Solution

10% in H₂O, PROTEIN GRADE^®

• Synonym(s): (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol solution, t-Octylphenoxypolyethoxyethanol; Polyethylene glycol tert-octylphenyl ether
• CAS Number: 9036-19-5
• Beilstein: 2315025
• MDL number: MFCD00128254
• UNSPSC Code: 12161902
• NACRES: NA.21

Properties

• product name: Triton^™ X-114, PROTEIN GRADE^® Detergent, 10% Solution, Sterile-Filtered, Non-ionic detergent and emulsifier. HLB 12.4. Cloud point 22°C.
• Quality Level: 100
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: <200 μM Aldehyde; <200 μM peroxide
• color: clear
• conductivity: <50 μmho
• CMC: 350 μM
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1
• InChI: 1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3
• InChI key: HNLXNOZHXNSSPN-UHFFFAOYSA-N

Description

General description

HLB 12.4. Cloud point 22°C.

Non–ionic detergent and emulsifier.

Non-ionic detergent and emulsifier (cloud point: 22°C; CMC: 350 µM; HLB: 12.4).

Application

• Determination of nine aromatic amines in water by cloud point extraction-gas chromatography-mass spectrometry.: This study utilized Triton X-114 for cloud point extraction to enhance the detection sensitivity of aromatic amines in water samples. The detergent played a crucial role in the efficient extraction and subsequent analysis of these compounds, highlighting its utility in environmental monitoring and analytical chemistry (Yang et al., 2024).


• An innovative lab-scale production for a novel therapeutic DNA vaccine candidate against rheumatoid arthritis.: Triton X-114 was employed in the purification steps to ensure the integrity and activity of the vaccine components. This detergent′s role in protein solubilization and membrane protein isolation was pivotal in the development of the therapeutic candidate, demonstrating its importance in biotechnological applications (Long et al., 2024).


• Lipoprotein signal peptidase-deficient Streptococcus pneumoniae exhibits impaired Toll-like receptor 2-stimulatory activity.: The study used Triton X-114 for the extraction and analysis of membrane proteins, which facilitated the investigation of bacterial interactions with host immune receptors. This application underscores the detergent′s effectiveness in microbial research and immunology (Domon et al., 2024).


• Improvement in the Chromium(VI)-Diphenylcarbazide Determination Using Cloud Point Microextraction; Speciation of Chromium at Low Levels in Water Samples.: Triton X-114 was used for cloud point extraction to improve the sensitivity and accuracy of chromium speciation in water samples. This method highlights the detergent′s role in environmental analytical chemistry, enhancing the detection of trace metal species (Mouco-Novegil et al., 2023).

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Physical form

A 10% aqueous solution.

Other Notes

D’Arrigo, A., et al. 1993. J. Biol. Chem.268, 2802.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

PROTEIN GRADE is a registered trademark of Merck KGaA, Darmstadt, Germany

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

Safety Information

• Pictograms: GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H315,H318,H410
• Precautionary Statements: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable