- Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cells.
Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cells.
Scientific reports (2017-06-10)
Shanel Dhani, Savania Nagiah, Dhaneshree B Naidoo, Anil A Chuturgoon
PMID28596589
ABSTRACT
Fusaric acid (FA), a food-borne mycotoxin, is a potent divalent metal chelator. The human immune system is complex and susceptible to environmental insult however, the immunotoxity of FA remains unknown. We investigated the immunotoxicity of FA on human peripheral blood mononuclear cells (PBMCs) and Thp-1 cells. FA was cytotoxic to PBMCs (IC
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Anti-p38 MAP Kinase, Activated (Diphosphorylated p38) antibody, Mouse monoclonal, clone P38-TY, purified from hybridoma cell culture, buffered aqueous solution
Sigma-Aldrich
Anti-β-Actin−Peroxidase antibody, Mouse monoclonal, clone AC-15, purified from hybridoma cell culture