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Merck

Thionyl-chloride-induced lung injury and bronchiolitis obliterans.

Chest (1993-09-01)
S Konichezky, A Schattner, T Ezri, P Bokenboim, D Geva
ABSTRACT

Thionyl-chloride (TCl) is used in the manufacture of lithium batteries, producing SO2 and HCl fumes on contact with water. We report two cases of accidental TCl exposure resulting in lung injury that may vary from a relatively mild and reversible interstitial lung disease to a severe form of bronchiolitis obliterans causing, after a latent period, an acute/chronic respiratory failure as well as other complications (spontaneous pneumothorax and bronchopleural fistula), previously unreported in TCl fume inhalation.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Thionyl chloride, ReagentPlus®, ≥99%
Sigma-Aldrich
Thionyl chloride, reagent grade, 97%