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  • Synthesis of indoles via domino reaction of N-aryl amides and ethyl diazoacetate.

Synthesis of indoles via domino reaction of N-aryl amides and ethyl diazoacetate.

Journal of the American Chemical Society (2008-09-19)
Sun-Liang Cui, Jing Wang, Yan-Guang Wang
PMID18798615
ABSTRACT

A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.

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E22201
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Ethyl diazoacetate, contains ≥13 wt. % dichloromethane
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