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  • Diversity-oriented approach to macrocyclic cyclophane derivatives by Suzuki-Miyaura cross-coupling and olefin metathesis as key steps.

Diversity-oriented approach to macrocyclic cyclophane derivatives by Suzuki-Miyaura cross-coupling and olefin metathesis as key steps.

The Journal of organic chemistry (2011-12-02)
Sambasivarao Kotha, Arjun S Chavan, Mobin Shaikh
ABSTRACT

Palladium-catalyzed Suzuki-Miyaura (SM) cross-coupling reaction with allylboronic acid pinacol ester and titanium assisted cross-metathesis (CM)/ring-closing metathesis (RCM) cascade has been used to synthesize macrocyclic cyclophane derivatives.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Allylboronic acid pinacol ester, 97%