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Merck

WNK4

WNK lysine deficient protein kinase 4

Synonyms:
PHA2B, PRKWNK4
Species:
UniProtKB ID:
Gene ID:
  • Human(65266) Summary: This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009]
  • Mouse(69847) WNK lysine deficient protein kinase 4
  • Rat(287715) WNK lysine deficient protein kinase 4
  • sheep(101111820) WNK lysine deficient protein kinase 4
  • domestic guinea pig(100719313) WNK lysine deficient protein kinase 4
  • dog(490959) WNK lysine deficient protein kinase 4
  • domestic cat(101100264) WNK lysine deficient protein kinase 4
  • cow(100849076) WNK lysine deficient protein kinase 4
  • Thale Cress(835947) putative serine/threonine-protein kinase WNK4
  • naked mole-rat(101722723) WNK lysine deficient protein kinase 4

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-WNK4 antibody produced in mouse, clone 1E6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-WNK4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human WNK4,
Species
human