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Merck

RAB3GAP1

RAB3 GTPase activating protein subunit 1 (catalytic)

Synonyms:
P130, RAB3GAP, RAB3GAP130, WARBM1
Species:
Human RAB3GAP1 (22930), Mouse Rab3gap1 (226407), Zebrafish rab3gap1 (777744), Horse RAB3GAP1 (100050665), cow RAB3GAP1 (535393), domestic cat RAB3GAP1 (101090959), dog RAB3GAP1 (476127), sheep RAB3GAP1 (101105474), chicken RAB3GAP1 (424290), naked mole-rat Rab3gap1 (101726563)
UniProtKB ID:
Q15042, Q659F5, Q8TBB4
Gene ID:
  • Human(22930) Summary: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
  • Mouse(226407) RAB3 GTPase activating protein subunit 1
  • Zebrafish(777744) RAB3 GTPase activating protein subunit 1
  • Horse(100050665) RAB3 GTPase activating protein subunit 1 (catalytic)
  • cow(535393) RAB3 GTPase activating protein subunit 1 (catalytic)
  • domestic cat(101090959) RAB3 GTPase activating protein subunit 1 (catalytic)
  • dog(476127) RAB3 GTPase activating protein subunit 1 (catalytic)
  • sheep(101105474) RAB3 GTPase activating protein subunit 1 (catalytic)
  • chicken(424290) RAB3 GTPase activating protein subunit 1 (catalytic)
  • naked mole-rat(101726563) RAB3 GTPase activating protein subunit 1 (catalytic)
  • domestic guinea pig(100732896) RAB3 GTPase activating protein subunit 1 (catalytic)

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA034494
Anti-RAB3GAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU007941
MISSION® esiRNA, targeting mouse Rab3gap1,
Species
mouse
EHU053091
MISSION® esiRNA, targeting human RAB3GAP1,
Species
human