NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Synonyms:
CI-75Kd, CI-75k, PRO1304
Species:
Human NDUFS1 (4719), Mouse Ndufs1 (227197), Rat Ndufs1 (301458), Zebrafish ndufs1 (493605), chicken NDUFS1 (424102), domestic guinea pig Ndufs1 (100726311), naked mole-rat Ndufs1 (101698993), cow NDUFS1 (288380), sheep NDUFS1 (101115434), Goat NDUFS1 (100861376) ...More
UniProtKB ID:
Gene ID:
- Human(4719) Summary: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
- Mouse(227197) NADH dehydrogenase (ubiquinone) Fe-S protein 1
- Rat(301458) NADH dehydrogenase (ubiquinone) Fe-S protein 1
- Zebrafish(493605) NADH dehydrogenase (ubiquinone) Fe-S protein 1
- chicken(424102) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- domestic guinea pig(100726311) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- naked mole-rat(101698993) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- cow(288380) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- sheep(101115434) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- Goat(100861376) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- domestic cat(101100747) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- dog(478880) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- Horse(100066330) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NDUFS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-NDUFS1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NDUFS1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NDUFS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-Complex I-75kD Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, chimpanzee, human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human