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Merck

GRIN2D

glutamate receptor, ionotropic, N-methyl D-aspartate 2D

Synonyms:
EB11, GluN2D, NMDAR2D, NR2D
Species:
UniProtKB ID:
Gene ID:
  • Human(2906) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
  • Mouse(14814) glutamate receptor, ionotropic, NMDA2D (epsilon 4)
  • Rat(24412) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • cow(618181) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • domestic cat(101095061) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • naked mole-rat(101710918) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • domestic guinea pig(100731717) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • dog(484405) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • sheep(101105943) glutamate receptor, ionotropic, N-methyl D-aspartate 2D

Custom & Knockdown Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
L-Tyrosine disodium salt hydrate, ≥98% (HPLC), powder,
Species
mouse, rat, human
D-Cycloserine, synthetic,
Species
human
Dextromethorphan hydrobromide monohydrate, ≥99% (TLC),
Species
human
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Species
human, rat
D-Cycloserine, ,
Species
human, mouse, rat

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
S-(+)-Ketamine hydrochloride, ,
Species
human
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Acamprosate calcium, ≥98% (HPLC), powder,
Species
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Arcaine sulfate salt, ,
Species
human
Ifenprodil (+)-tartrate salt, ,
Species
human
D(−)-2-Amino-5-phosphonopentanoic acid, NMDA receptor antagonist,
Species
mouse, rat
Felbamate, ,
Species
human
(±)-2-Amino-4-phosphonobutyric acid, solid,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NMDAR2D Antibody, ascites fluid, clone 1G9.39A5, Chemicon®,
Species Reactivity
human, mouse, rabbit, rat
Application
western blot
Anti-GRIN2D antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Species
human
Agmatine sulfate salt, ≥97%, powder,
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Pentamidine isethionate salt, powder,
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Grin2d,
Species
mouse
MISSION® esiRNA, targeting human GRIN2D,
Species
human