ERVW-1
endogenous retrovirus group W, member 1
Synonyms:
ENV, ENVW, ERVWE1, HERV-7q, HERV-W-ENV, HERV7Q, HERVW, HERVWENV
Species:
UniProtKB ID:
Gene ID:
- Human(30816) Summary: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ERVW-1 (N-terminal) antibody produced in rabbit biotin conjugated, affinity isolated antibody,
Species Reactivity
human, rat
Application
Anti-ERVW-1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Species Reactivity
human, rat
Application
Anti-ERVW-1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Species Reactivity
human, rat
Application
Anti-ERVW-1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, rat
Application
western blot
esiRNA
Product Number
Description
Species