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Merck

ACVR1B

activin A receptor, type IB

Synonyms:
ACTRIB, ACVRLK4, ALK4, SKR2
Species:
UniProtKB ID:
Gene ID:
  • Human(91) Summary: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
  • Mouse(11479) activin A receptor, type 1B
  • Rat(29381) activin A receptor, type IB
  • chicken(768878) activin A receptor, type IB
  • sheep(443254) activin A receptor, type IB
  • naked mole-rat(101709452) activin A receptor, type IB
  • dog(486537) activin A receptor, type IB
  • sheep(101113836) activin A receptor, type IB
  • cow(539315) activin A receptor, type IB
  • Horse(100062619) activin A receptor, type IB
  • Zebrafish(30183) activin A receptor, type IB
  • domestic cat(101097654) activin A receptor, type IB
  • domestic guinea pig(100733441) activin A receptor, type IB

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ELISA

Product Number
Description
Species
Human Activin R1B ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ACVR1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ACV1B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-ACVR1B antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-ACVR1B antibody produced in mouse, clone 2D4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-ACVR1B antibody produced in mouse, clone 1C1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay

western blot

Proteins

Product Number
Description
Species
ALK4 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human ALK4 amino acids 150-end. For use in Kinase Assays.,
Species
human
ALK4 (150-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Acvr1b,
Species
mouse
MISSION® esiRNA, targeting human ACVR1B,
Species
human