Skip to Content
Merck
  • Dispersion of titanate nanotubes for nanomedicine: comparison of PEI and PEG nanohybrids.

Dispersion of titanate nanotubes for nanomedicine: comparison of PEI and PEG nanohybrids.

Dalton transactions (Cambridge, England : 2003) (2014-11-20)
Anne-Laure Papa, Julien Boudon, Vanessa Bellat, Alexis Loiseau, Harender Bisht, Fadoua Sallem, Rémi Chassagnon, Véronique Bérard, Nadine Millot
PMID25408156
ABSTRACT

In the present study, we report the dispersion of titanate nanotubes (TiONts) via polymer grafting (PolyEthylene Glycol, PEG) or polymer adsorption (polyethylene imine, PEI) where different TiONts/polymer ratios have been investigated. The TiONts/PEI and TiONts/PEG nanohybrids were characterized by scanning and transmission electron microscopy as well as by zeta potential measurements in order to determine both their dispersion state and stability in water (at different pH for zetametry). The nature of the chemical bonds at the surface of these nanohybrids was investigated by Fourier-transformed infrared (FTIR) spectroscopy while the grafting densities of PEG on the nanotubes were quantified by thermogravimetric analyses (TGA). The nanohybrids reported here are promising tools for biotechnology applications due to their tubular morphology, their very good dispersion in water and the reactivity of their surface.

MATERIALS
Product Number
Brand
Product Description
705551
Sigma-Aldrich
Hydrogen chloride solution, 3 M in cyclopentyl methyl ether (CPME)
17933
Supelco
Hydrogen chloride – 2-propanol solution, ~1.25 M HCl (T), for GC derivatization, LiChropur™
H1758
Sigma-Aldrich
Hydrochloric acid, 36.5-38.0%, BioReagent, for molecular biology
2104
Supelco
Hydrochloric acid solution, volumetric, 0.1 M HCl (0.1N), endotoxin free
H9892
Sigma-Aldrich
Hydrochloric acid solution, 1.0 N, BioReagent, suitable for cell culture
78445
Supelco
Tetrahydrofuran, analytical standard
87369
Supelco
Tetrahydrofuran, Selectophore™, ≥99.5%
21049
Supelco
Calcium standard for AAS, analytical standard, 1.000 g/L Ca+2 in hydrochloric acid, traceable to BAM
17935
Supelco
Hydrogen chloride – methanol solution, ~1.25 m HCl (T), for GC derivatization, LiChropur™
17934
Supelco
Hydrogen chloride – ethanol solution, ~1.25 M HCl, for GC derivatization, LiChropur™
291234
Sigma-Aldrich
Dibutyltin dilaurate, 95%
84429
Sigma-Aldrich
Hydrochloric acid solution, ~6 M in H2O, for amino acid analysis
PHR1561
Supelco
Tetrahydrofuran, Pharmaceutical Secondary Standard; Certified Reference Material
W530574
Sigma-Aldrich
Hydrochloric acid solution, 32 wt. % in H2O, FCC
34865
Sigma-Aldrich
Tetrahydrofuran, inhibitor-free, suitable for HPLC, ≥99.9%
339253
Sigma-Aldrich
Hydrochloric acid, 37 wt. % in H2O, 99.999% trace metals basis
320331
Sigma-Aldrich
Hydrochloric acid, ACS reagent, 37%
258148
Sigma-Aldrich
Hydrochloric acid, ACS reagent, 37%
360589
Sigma-Aldrich
Tetrahydrofuran, contains 250 ppm BHT as inhibitor, ACS reagent, ≥99.0%
676764
Sigma-Aldrich
Tetrahydrofuran, ACS reagent, ≥99.0%, contains 250 ppm BHT as inhibitor
S2770
Sigma-Aldrich
Sodium hydroxide solution, 1.0 N, BioReagent, suitable for cell culture
72064
Supelco
Sodium hydroxide solution, 49-51% in water, eluent for IC
M2128
Sigma-Aldrich
Thiazolyl Blue Tetrazolium Bromide, 98%
282979
Sigma-Aldrich
3-Ethyl-2,4-pentanedione, mixture of tautomers, 98%
655104
Sigma-Aldrich
Sodium hydroxide, reagent grade, 97%, powder
345547
Sigma-Aldrich
Hydrogen chloride solution, 4.0 M in dioxane
07102
Sigma-Aldrich
Hydrochloric acid, meets analytical specification of Ph. Eur., BP, NF, fuming, 36.5-38%
M5655
Sigma-Aldrich
Thiazolyl Blue Tetrazolium Bromide, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC)
757527
Sigma-Aldrich
Sodium hydroxide, ultra dry, powder or crystals, 99.99% trace metals basis
71687
Sigma-Aldrich
Sodium hydroxide, BioUltra, for luminescence, ≥98.0% (T), pellets