- Regioselective palladium-catalyzed arylation of 3-carboalkoxy furan and thiophene.
Regioselective palladium-catalyzed arylation of 3-carboalkoxy furan and thiophene.
Organic letters (2003-01-31)
Bobby Glover, Kimberly A Harvey, Bing Liu, Matthew J Sharp, Maria F Tymoschenko
PMID12556177
ABSTRACT
[reaction: see text] The regioselective palladium(0)-catalyzed arylation of 3-furoate and 3-thiophenecarboxylate esters with aryl bromides is described. Conditions were developed that allow for the selective synthesis of either 2-aryl or 5-aryl products.
MATERIALS