- Efficient construction of fused indolines with a 2-quaternary center via an intramolecular Heck reaction with a low catalyst loading.
Efficient construction of fused indolines with a 2-quaternary center via an intramolecular Heck reaction with a low catalyst loading.
Organic letters (2012-04-03)
Lei Zhao, Ziyuan Li, Lin Chang, Jinyi Xu, Hequan Yao, Xiaoming Wu
PMID22463710
ABSTRACT
An efficient construction of fused indolines with a 2-quaternary center through a palladium-catalyzed intramolecular Heck reaction of N-(2(2-halobenzoxyl)-2,3-disubstituted indoles is disclosed. This protocol provided a straightforward access to diverse fused indolines with good functional group tolerance.
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