- In vitro activity of thimerosal against ocular pathogenic fungi.
In vitro activity of thimerosal against ocular pathogenic fungi.
Antimicrobial agents and chemotherapy (2009-10-21)
Yan Xu, Guangren Pang, Dongqing Zhao, Chuanwen Gao, Lutan Zhou, Shengtao Sun, Bingliang Wang
PMID19841144
ABSTRACT
The in vitro activity of thimerosal versus those of amphotericin B and natamycin was assessed against 244 ocular fungal isolates. The activity of thimerosal against Fusarium spp., Aspergillus spp., and Alternaria alternata was 256 times, 512 times, and 128 times, respectively, greater than that of natamycin and 64 times, 32 times, and 32 times, respectively, greater than that of amphotericin B. Thimerosal's antifungal activity was significantly superior to those of amphotericin B and natamycin against ocular pathogenic fungi in vitro.