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Merck

UBE2D3

ubiquitin-conjugating enzyme E2D 3

Synonyms:
E2(17)KB3, UBC4/5, UBCH5C
Species:
UniProtKB ID:
Gene ID:
  • Human(7323) Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(66105) ubiquitin-conjugating enzyme E2D 3
  • Rat(81920) ubiquitin-conjugating enzyme E2D 3
  • domestic cat(101094845) ubiquitin-conjugating enzyme E2D 3
  • chicken(422713) ubiquitin-conjugating enzyme E2D 3
  • Zebrafish(321832) ubiquitin-conjugating enzyme E2D 3
  • domestic guinea pig(100730907) ubiquitin-conjugating enzyme E2D 3
  • naked mole-rat(101725641) ubiquitin-conjugating enzyme E2D 3
  • cow(326583) ubiquitin-conjugating enzyme E2D 3
  • sheep(101107195) ubiquitin-conjugating enzyme E2D 3

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-UBE2D3 antibody produced in mouse, clone S2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-UBE2D3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
western blot
Anti-UBE2D3, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human UBE2D3,
Species
human
MISSION® esiRNA, targeting mouse Ube2d3,
Species
mouse