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Merck

SFRP1

secreted frizzled-related protein 1

Synonyms:
FRP, FRP-1, FRP1, FrzA, SARP2
Species:
UniProtKB ID:
Gene ID:
  • Human(6422) Summary: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
  • Mouse(20377) secreted frizzled-related protein 1
  • Rat(84402) secreted frizzled-related protein 1
  • cow(282068) secreted frizzled-related protein 1
  • sheep(101121066) secreted frizzled-related protein 1
  • dog(482844) secreted frizzled-related protein 1
  • domestic cat(101083585) secreted frizzled-related protein 1
  • chicken(395237) secreted frizzled-related protein 1
  • naked mole-rat(101716300) secreted frizzled-related protein 1
  • domestic guinea pig(100727192) secreted frizzled-related protein 1

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ELISA

Product Number
Description
Species
Human sFRP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SFRP1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SFRP1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, guinea pig, horse, human, mouse, rat
Application
western blot
Anti-SFRP1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, mouse
Application
ELISA
immunohistochemistry
Anti-SFRP1 Antibody, clone 5I6V1, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-sFRP-1 Antibody, from rabbit,
Species Reactivity
human, mouse
Application
immunohistochemistry
neutralization

western blot

Proteins

Product Number
Description
Species
sFRP-1 human, recombinant, expressed in HeLa cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SFRP1,
Species
human
MISSION® esiRNA, targeting mouse Sfrp1,
Species
mouse