DUX4
double homeobox 4
Synonyms:
DUX10
Species:
UniProtKB ID:
Gene ID:
- Human(22947) Summary: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of this gene from standard cDNA libraries, however, RT-PCR and in vitro expression experiments indicate that the ORF is transcribed. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the microsatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, May 2013]
- dog(491532) uncharacterized LOC491532
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-DUX4 antibody produced in mouse, clone P2B1, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-DUX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Dux4 Antibody, clone 9A12, clone 9A12, from mouse,
Species Reactivity
human
Application
electrophoretic mobility shift assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species