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Merck

CLEC7A

C-type lectin domain family 7, member A

Synonyms:
BGR, CANDF4, CLECSF12, DECTIN1
Species:
UniProtKB ID:
Gene ID:
  • Human(64581) Summary: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
  • Mouse(56644) C-type lectin domain family 7, member a
  • Rat(502902) C-type lectin domain family 7, member A
  • domestic cat(101083523) C-type lectin domain family 7, member A
  • dog(611385) C-type lectin domain family 7, member A
  • cow(532865) C-type lectin domain family 7, member A
  • sheep(678685) C-type lectin domain family 7, member A
  • domestic guinea pig(100725843) C-type lectin domain family 7, member A
  • naked mole-rat(101708518) C-type lectin domain family 7, member A

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ELISA

Product Number
Description
Species
Human Dectin-1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CLEC7A antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CLEC7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Clec7a,
Species
mouse
MISSION® esiRNA, targeting human CLEC7A,
Species
human