Clinical & Forensic Testing

Benefits

• Superior patient care and safety: comprehensive range of trusted, innovative LC-MS diagnostic solutions for accurate results
• Greater quality control: batch-to-batch consistency, product quality verification, and detection of contaminants or impurities
  
• Up to date regulations: extensive technical content and global support on drug efficacy, toxicity, and pharmacokinetics
  
• Speed and convenience: all the products you need available 24/7 on our e-commerce platform with fast, reliable delivery

Clinical Testing Techniques

Select your preferred diagnostic method to review its workflow and directly purchase analytical products.

• LC-MS-Based Clinical Testing
• PCR-Based Clinical Testing
• ELISA-Based Clinical Testing
  

LC-MS is a powerful analytical technique used more and more in clinical laboratories to analyze complex mixtures and identify and quantify various substances, such as drugs, metabolites, and biomarkers, in patient samples. It offers, often in combination with distinct and robust sample preparation techniques -depending on sample and analyte type, high sensitivity, selectivity, allowing for accurate and fast results for targeted determinations and screenings. LC-MS is particularly valuable in detecting low concentrations of analytes and in identifying unknown compounds, making it an essential tool for enhancing patient care and improving treatment outcomes in today's clinical labs in hospitals. Fundament for reliable results are suitable standards such as certified reference materials to ensure accurate identifications and quantifications. 

Applications

• Therapeutic drug monitoring
• Hormone screening
• Vitamin testing
• Drugs of abuse testing          
• Metabolic analysis        
• Newborn screening

Clinical PCR testing is a widely used technique to detect and analyze the presence, length, or sequence of DNA or RNA from biological samples for diagnostic purposes. While identifying pathogens, genetic mutations, or other molecular markers is the most common use, clinical PCR has broader applications. It plays a crucial role in treatment monitoring, personalized medicine, cancer care, and other healthcare applications.

The PCR workflow starts with sample collection, followed by sample preparation, and concludes with DNA/RNA target-specific amplification. Typically, the post-amplification analysis is performed using qPCR, where quantification occurs in real time during the amplification cycles. Alternatively, end-point PCR can be used, where results are measured after the amplification cycles are complete. A key goal in preparing a DNA or RNA library for next generation sequencing (NGS) is to maximize its complexity while minimizing biases introduced by PCR or other amplification methods, as these factors significantly influence the quality of the resulting library and, ultimately, the NGS results.

Applications

• Infectious disease screening and identification
• Clinical Genomics
• Genetic screening
• Oncology
• Prenatal testing

Enzyme-linked immunosorbent assay (ELISA) is an immunoassay technique widely used for high-throughput screening and quantification of antibodies, proteins, peptides, and other small molecules. ELISAs are typically run on a 96-well plate format. Plates can be supplied ready to use for in vitro diagnostics (IVDs) or prepared in-house for lab-developed tests (LDTs).

Applications

• Oncology
• Infectious diseases
• Drugs of abuse screening
• Hormone measurement
• Immune function/immunology