1486004

Oxymetazoline hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 2-(3-Hydroxy-2,6-dimethyl-4-t-butylbenzyl)-2-imidazoline hydrochloride
• Empirical Formula (Hill Notation): C₁₆H₂₄N₂O · HCl
• CAS Number: 2315-02-8
• Molecular Weight: 296.84
• MDL number: MFCD00058147
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750645
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: oxymetazoline
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• InChI key: BEEDODBODQVSIM-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Oxymetazoline hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Oxymetazoline Hydrochloride Ophthalmic Solution
• Oxymetazoline Hydrochloride Nasal Solution

Biochem/physiol Actions

Oxymetazoline hydrochloride is a partial α_2A-adrenoceptor agonist; agonist at 5-HT_1A, 5-HT_1B, and 5-HT_1D serotonin receptors. It is a mixed agonist-antagonist at 5-HT_1C serotonin receptors.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H300 + H330,H318,H412
• Precautionary Statements: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• Storage Class Code: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable