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USP

Ciprofloxacin hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Ciprofloxacin hydrochloride monohydrate

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About This Item

Empirical Formula (Hill Notation):
C17H18FN3O3 · HCl · H2O
CAS Number:
Molecular Weight:
385.82
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ciprofloxacin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O.Cl.OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O

InChI

1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2

InChI key

ARPUHYJMCVWYCZ-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application


  • Antibacterial applications in poultry: A study investigating Escherichia coli isolates from broilers with cellulitis highlights ciprofloxacin′s role in treating bacterial infections in poultry, emphasizing its effectiveness in agricultural antibiotic practices and its impact on animal health (Müller et al., 2024).

  • Nanocarrier drug delivery: Research on pH-sensitive nanocarriers for ciprofloxacin delivery discusses the development of chitosan-g-poly(itaconic acid) based systems, showcasing advanced drug delivery technologies that enhance the efficacy of antibiotics like ciprofloxacin in combating resistant bacterial strains (Kumar and Kumar, 2024).

  • Photocatalytic decontamination: A study on Fe-O-Bi electron migration in a Z-scheme heterojunction for photocatalytic decontamination underscores the broader applications of ciprofloxacin beyond its primary use, providing insights into environmental management of pharmaceutical pollutants (Song et al., 2024).

  • Endodontic applications: A case report on the atypical healing of an endodontic lesion following emergency treatment with ciprofloxacin provides valuable data on its application in dental care, particularly in managing infections post-dental procedures (Asgary and Talebzadeh, 2024).

  • Hospital-acquired infections: Genomic characterization of methicillin-resistant Staphylococcus aureus in a hospital setting discusses the role of antibiotics like ciprofloxacin in controlling outbreaks, highlighting the importance of molecular studies in understanding and managing hospital-acquired infections (Huang et al., 2024).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Andrea Meyerhoff et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 39(3), 303-308 (2004-08-13)
In August 2000, the US Food and Drug Administration (FDA) approved ciprofloxacin hydrochloride (Cipro; Bayer) for management of postexposure inhalational anthrax. This was the first antimicrobial drug approved by the FDA for use in treating an infection due to a
Lucile Pantel et al.
Antimicrobial agents and chemotherapy (2021-03-10)
NOSO-502 is a preclinical antibiotic candidate of the Odilorhabdin class. This compound exhibits activity against Enterobacteriaceae pathogens, including carbapenemase-producing bacteria and most of the Colistin (CST)-resistant strains. Among a collection of CST-resistant Klebsiella pneumoniae strains harboring mutations on genes pmrAB
Tarek Haddad et al.
Chemosphere, 115, 40-46 (2014-03-19)
The presence of pharmaceuticals, especially antibiotics, in the aquatic environment is of growing concern. Several studies have been carried out on the occurrence and environmental risk of these compounds. Ciprofloxacin (CIP), a broad-spectrum anti-microbial second-generation fluoroquinolone, is widely used in
Corinne N Thompson et al.
Tropical medicine & international health : TM & IH, 19(10), 1284-1292 (2014-07-30)
The country of Fiji, with a population of approximately 870 000 people, faces a growing burden of several communicable diseases including the bacterial infection typhoid fever. Surveillance data suggest that typhoid has become increasingly common in rural areas of Fiji
Aaron Butt et al.
The Biochemical journal, 459(2), 333-344 (2014-02-08)
TA (toxin-antitoxin) systems are widely distributed amongst bacteria and are associated with the formation of antibiotic tolerant (persister) cells that may have involvement in chronic and recurrent disease. We show that overexpression of the Burkholderia pseudomallei HicA toxin causes growth

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